kicked off her three-night Greatest Night Of Giveaways on Tuesday with the help of who got emotional while helping a family.
Jennifer, 50, broke down in tears watching a video of a daughter pleading with Ellen, 61, to help her unemployed father.
Viewer Elyse Kimball made the video about her dad Jeff who lost his wife and mother of their two daughters to cancer when the girls were young.
Charity: kicked off her three-night Greatest Night Of Giveaways with Jennifer and it all got a little too much
She said: 'He has given all he has got for our family of three. He doesn't deserve this,' Elyse said weeping in the video.
'He's all I got. He is my life. He is what gets me through the good and the bad. For once, I want to give something to him. I want him to get something he deserves, and I can't do this without help,' she added tearfully.
The video made Jennifer cry and Ellen surprised the family by sending a film crew pretending to do a show about people who turn their lives around.
Jeff Kimball in a video package spoke of losing his wife Amy when Elyse was only three and her sister Lexi was age five.
He and his daughters were shown in the studio audience and were invited up by Ellen as Jennifer wiped away tears and also helped Elyse with her wet eyes.
Jeff shared that Ellen's character Dory from Finding Nemo inspired Amy's battle against cancer.
'She was going in for a 13-hour surgery. The last thing I did was blow her a kiss and say, ''Just keep swimming'',' he said.
'Oh, my God!,' Jennifer exclaimed. 'What would your mom say right now if she knew you guys were here?'
'She would be so happy. Ellen, she was your biggest fan. So, she would be like, ''Move over, 'cause I am getting closer'',' Jeff said.
Ellen then revealed that while they were away for the taping that their house had been decorated with Christmas lights.
Their home also was filled with a Christmas tree, multiple presents and updated furniture.
Jennifer also gifted the family with an ornament for the Christmas tree of the Eiffel Tower.
The Friends star revealed that it was on Amy's bucket list to take a trip to Paris. Ellen then announced she was sending the family to the French capital for a vacation.
Jennifer said she was in Italy recently and added the destination to their itinerary.
Ellen said they should also go to London and Jennifer said they 'might as well go to Greece'.
'You're going to Europe for a month,' Ellen told the excited family.
The family later played a version of the telephone game called Say Whaaat? and each of them were gifted $50,000 in Visa cards.
The premiere episode opened with Michelle Obama, 55, surprising students at Randle Highlands Elementary School in southeast Washington, DC.