The actors who play the married couple, Jamie Reagan and Eddie Janko, on the show "Blue Bloods" are actually friends in real life. Vanessa Ray, who plays Eddie, shared an anecdote about how she and Will Estes, who plays Jamie, were always talking and had a strong friendship on and off-camera. She described their friendship as one of her longest relationships and mentioned that they know each other in a very specific way due to working together for many years. This close bond between the actors contributes to their strong on-screen chemistry.